1. 제 목 : Probe-based optical imaging - toward in vivo translational study
2. 연 사 : 정 웅 규 교수(울산과기대 나노바이오화학공학부)
3. 일 시 : 2012년 4월 13일 (금) 16:30-17:30
4. 장 소 : 301동 105호
5. 내용 :
Probe-based imaging means minimally invasive, portable and fast imaging techniques for diagnosing diseases or monitoring tissues. It requires practical performances such high resolution, real time visualization of specific tissue regions rather than full visualization of large area. The concept of probe-based imaging is getting important, and is used very broadly, because continuous tissue monitoring can provide accurate diagnosis, clear determination of the surgical area, and confirmation of the surgical margin after a procedure.
Optical imaging inherently offers many advantages which are well suited for probe-based imaging: (1) higher spatial resolution and sensitivity, (2) tissue and molecular information based on scattering, absorption, and fluorescence, (3) availability of contrast agents for specific targeted biomarkers, and (4) lower costs. Furthermore, implementation using fiber optics can offer portability and accessibility for in vivo applications. Thus, optical imaging technique has a potential to provide ideal platform for probe-based diagnostics and image-guided treatments. However, translation from laboratory settings to clinical environment poses unique engineering challenges such as miniaturization of probes, real-time speed requirements. Solving these challenges often requires the state-of-the-art tools including micro-optics and MEMS technologies.
This presentation covers the latest work of probe-based high resolution optical imaging using optical coherence tomography (OCT) and multiphoton microscopy (MPM) for in vivo clinical applications. Specifically, the talk will highlight handheld OCT for primary care medicine and fiber based compact MPM. Long term objective of these researches is to use complementary imaging systems to better assess the biological specimen and to enable clinical diagnosis.
6. 연사약력 :
Woonggyu Jung received his Ph. D. in 2008 from the Department of Biomedical Engineering at the University of California, Irvine. From 2001 to 2008, he worked at the Beckman Laser Institute and Medical Clinic at UC Irvine, which is one of the world’s top research organizations in laser treatment and diagnosis. He worked at the Beckman Institute for Advanced Science and Technology at the University of Illinois at Urbana-Champaign since January 2009. He joined the faculty of UNIST in 2012 as an assistant professor of school of Nano-Bioscience & Chemical Engineering.
Dr. Jung has a strong research background in optical imaging technologies including optical coherence tomography (OCT), multiphoton microscopy (MPM), and miniaturized optical imaging probes. His research interest is to develop new optical technologies that address challenges in clinical medicine and basic biological research. His long-term goal is to pursue implementation of research tools for in vivo translational studies, where functionalities such as real-time measurement, compactness and portability are essential. In previous work, he developed a successful platform of probe-based compact optical imaging systems for in vivo translational research, and has published more than 30 peer-reviewed journal papers in the field of biophotoics.
7. 문 의 : 기계항공공학부 김호영 교수 (hyk@snu.ac.kr)