1. 제 목 : Microfluidic Lab-on-a-Chip Systems for High- Throughput Screening in Microbial Bioenergy Systems

2. 연 사 : Prof. Arum Han, Texas A&M University
             (Dept. Electrical and Computer Engineering & Dept. Biomedical Engineering)

3. 일 시: 2013년 10월 18일 (금) 16:30-17:30

4. 장 소 : 301동 105호

5. 내 용
  Microfluidics that can accurately control extremely small amount of liquid samples together with various micro/nano fabrication technologies enable the concept of lab-on-a-chip systems. Our lab is interested in solving grand challenge problems in the broad area of health and energy through the use of micro/nano systems technology. Research themes in our lab range from developing organ-on-a-chip systems, developing systems for high-throughput single-cell physiochemical analysis of cancer cells, systems that enable us to understand physiology and functions in infectious disease, to systems that enable the concept of microbial biorefinary.
 The focus of this presentation will be on the concept of microbial biorefinary, and how microfluidic lab-on-a-chip systems can accelerate R&D in this emerging field of next-generation bioenergy production. Microalgae are envisioned as a future source of renewable oil. The feasibility of producing transportation grade hydrocarbons from microalgae is strongly dependent on developing better algal strains, understanding algal gene regulation, and optimizing growth conditions for higher oil production. Three examples of microfluidics-based systems that aims to significantly improve the algae to biofuel development pipeline will be presented. The first example is a high-throughput photobioreactor array as a photosynthetic organism screening/analyses platform that is currently being used to identify and define metabolic processes and genetic constraints that significantly enhance oil production and growth of microalgae. The second example is a microfluidic single-cell screening/selection platform that allows selecting cells of interest from a large library of genetically engineered or mutagenized microalgae. The third example is a droplet microfluidics based algal screening platform for rapid screening of algal library generated through genetic, metabolic, and mutagenic engineering. We believe that microfluidics and lab-on-a-chip platforms will be key technologies in bringing algal biofuel as a economically feasible next-generation transportation fuel.

6. 약 력
  Dr. Arum Han is an Associate Professor in the Department of Electrical and Computer Engineering and also in the Department of Biomedical Engineering at Texas A&M University (USA). He joined Texas A&M University in 2005 as an Assistant Professor.  He is also a faculty of Texas A&M Health Science Center and the Texas A&M Institute for Neuroscience. He received his Ph. D in electrical engineering from the Georgia Institute of Technology in 2005, his M.S. from the University of Cincinnati in 2000, and his B.S. from the Seoul National University in 1997, all in electrical engineering. His research interest is in solving grand challenge problems in the broad area of health and energy through the use of micro/nano systems technology and multidisciplinary team approach.
  He is the coauthor of over 80 peer-reviewed publications and serves as the editorial board member of the journal PLoS ONE. His research is supported by the Bill and Melinda Gates Foundation, National Institutes of Health (NIH), National Science Foundation (NSF), Defense Threat Reduction Agency (DTRA), United States Department of Agriculture (USDA), U.S. Army Corp of Engineers, Qatar National Research Foundation (QNRF), Korean Ministry of Knowledge Economy, and several private companies. He currently has 10 active funded projects. He is a Texas A&M Engineering Experiment Station (TEES) Fellow and recipient of the Department of Electrical and Computer Engineering Outstanding Professor Award in 2012.

7. 문 의 : 기계항공공학부 전누리 교수(njeon@snu.ac.kr), 김도년 교수(dnkim@snu.ac.kr)